Protein complexes 'inflammasomes' are linked to obesity-related colon cancer

Research presented at this year's European Congress on Obesity has reported that structures called inflammasomes (a part of the innate immune system that helps to regulate inflammation) could play an important role in the development of obesity-associated colon cancer. The study is by Dr Victoria Catalán and Professor Gema Frühbeck, University Hospital Navarra and CIBEROBN, Instituto de Salud Carlos III, Pamplona, Spain, and colleagues.

Cancer is not a disease of the genome, but genomes

Researchers at the Cancer Research UK Beatson Institute, led by Dr Payam Gammage, and in collaboration with scientists at the Memorial Sloan Kettering Cancer Center in the US led by Dr Ed Reznik, have revealed the substantial impact mutations in mitochondrial DNA (mtDNA) can have in cancer. Understanding this could offer up new indicators of disease prognosis and provide a new focus for future therapeutics.

Sugar-sweetened drinks associated with increased risk of CRC in women under 50

Researchers from Washington University School of Medicine in St. Louis has found a link between drinking sugar-sweetened beverages and an increased risk of developing colorectal cancer in women under age 50. The findings suggest that heavy consumption of sugary drinks during adolescence (ages 13 to 18) and adulthood can increase the disease risk.