Outcomes of natural orifice specimen extraction surgery (NOSES) for CRC

With the rapid development of minimally invasive surgery for the treatment of colorectal diseases, novel surgical techniques aiming at reducing surgical trauma have become frequently discussed issues. By avoiding auxiliary abdominal incision for specimen extraction, natural orifice specimen extraction surgery (NOSES), including transvaginal specimen extraction (TVSE) and transanal specimen extraction (TASE), is thought to be one of the least invasive options in the treatment of colorectal cancer (CRC).

Directing chemotherapy to ctDNA-positive patients reduces overall chemotherapy use

A study showed that circulating tumour DNA (ctDNA) - genetic material shed from tumours into the bloodstream - can identify stage II colon cancer patients who can most benefit from chemotherapy following surgery and spare other patients the need for this form of treatment.